Skip to main content Skip to main navigation menu Skip to site footer

Aggressive sinonasal angiomyxoma management with endoscopic medial maxillectomy approach: a rare case report

  • Mohammad Husni Thamrin ,
  • Budi Sutikno ,


Link of Video Abstract:


Background: Aggressive angiomyxoma is a benign tumour of mesenchymal origin, and its incidence is very rare. The treatment of choice for aggressive sinonasal angiomyxoma is surgical extirpation based on the location of the tumour. The surgical procedure can be performed endoscopically or externally. This study aims to report the management of an aggressive sinonasal angiomyxoma rare case with an endoscopic approach.

Case presentation: A 20-year-old female came with the chief complaint of a blocked right nose for the past six months. Patients often had varying amounts of intermittent epistaxis from the right nose, which could stop by itself but in a longer time. Three studies met the inclusion criteria and stated that aggressive sinonasal angiomyxoma is rare. Extirpation surgery was performed with an endoscopic medial maxillectomy approach. Histopathology showed a benign mesenchymal cell tumour consistent with angiomyxoma.

Conclusion: The sinonasal tumour with an early preoperative diagnosis of an antrochoanal polyp and a postoperative diagnosis of an aggressive sinonasal angiomyxoma underwent extirpation surgery with an endoscopic medial maxillectomy approach results in no recurrences after two years.


  1. Cao Z, Miao L, Liu M, et al. Aggressive angiomyxoma: The first case report in skull. Front Surg. 2022;9:985739.
  2. Aminimoghaddam S, Sarchami N, Mahboub SS. Second recurrence of aggressive vulvar angiomyxoma: a case report. J Int Med Res. 2023;51(8):3000605231189366.
  3. Kharbouch J, Aziz Z, Benzenzoum Z, et al. Maxillary and mandibular odontogenic myxomas: case report. Pan Afr Med J. 2022;42:103.
  4. Ramesh S, Govindraju P, Pachipalusu B. Odontogenic myxoma of posterior maxilla - A rare case report. J Family Med Prim Care. 2020;9(3):1744-1748.
  5. Gulino FA, Gulisano M, Ettore C, Giorlandino A, Russo E, Ettore G. Aggressive Angiomyxoma of the Vulva: Which Is the Best Management Strategy? Description of a Case Report and Review of Literature of the Last Ten Years. J Clin Med. 2023;12(5):1726.
  6. Perdana RF. Transnasal esophagoscopy examination in Outpatient Unit, Department of Otorhinolaryngology, Head and Neck surgery, Dr. Soetomo Hospital Surabaya. Folia Medica Indonesia. 2020;56(1):75-81.
  7. Banasser AM, Bawazir MM, Islam MN, Bhattacharyya I, Cohen DM, Fitzpatrick SG. Odontogenic Myxoma: A 23-Year Retrospective Series of 38 Cases. Head Neck Pathol. 2020;14(4):1021-1027.
  8. Ngham H, Elkrimi Z, Bijou W, et al. Odontogenic myxoma of the maxilla: A rare case report and review of the literature. Ann Med Surg (Lond). 2022;77:103575.
  9. Lee DH, Lim HR, Lee JK, Lim SC. Infrastructure maxillectomy for maxillary sinus and hard palate neoplasms. Mol Clin Oncol. 2021;15(3):180.
  10. Kawasumi T, Takeno S, Ishikawa C, et al. The Functional Diversity of Nitric Oxide Synthase Isoforms in Human Nose and Paranasal Sinuses: Contrasting Pathophysiological Aspects in Nasal Allergy and Chronic Rhinosinusitis. Int J Mol Sci. 2021;22(14):7561.
  11. Davidson T, Nissan J, Krichmar M, et al. 18F-FDG PET-CT postoperative changes after maxillectomy: Findings and pitfalls in interpretation. Dentomaxillofac Radiol. 2021;50(7):20200574.
  12. Airlangga PA, Lisan RA, Hidayat AR. Spinal Dural Arteriovenous Fistula in a Pediatric Patient With History of Endovascular Therapy Failure: A Case Report. Surabaya Physical Medicine and Rehabilitation Journal. 2023;5:2
  13. Buurman DJM, Speksnijder CM, Engelen BHBT, Kessler P. Masticatory performance and oral health-related quality of life in edentulous maxillectomy patients: A cross-sectional study to compare implant-supported obturators and conventional obturators. Clin Oral Implants Res. 2020;31(5):405-416.
  14. Patel N, Mel A, Patel P, Fakkhruddin A, Gupta S. A Novel Method to Rehabilitate Post-mucormycosis Maxillectomy Defect by Using Patient-Specific Zygoma Implant. J Maxillofac Oral Surg. 2023;22(Suppl 1):118-123.
  15. Sutikno B, Fauzi F, Ardani DM, Mailasari A. Differences in the length of postoperative care of endoscopic endonasal surgery in simple and complex surgical procedure groups. F1000Res. 2022;11:619.
  16. Singh M, Kapoor S, Kumar L, Pal US, Singh A, Anwar M. Prevalence of maxillectomy defects among patients visiting in an institutionalized hospital setting: A prospective, single-institute study. Natl J Maxillofac Surg. 2020;11(2):231-235.
  17. Ummah K, Adi S. Management of Residual Pituitary Adenoma Patient with Manifestation of Acromegaly and Hyperprolactinemia. Current Internal Medicine Research and Practice Surabaya Journal. 2021;2:2.

How to Cite

Thamrin, M. H. ., & Sutikno, B. (2024). Aggressive sinonasal angiomyxoma management with endoscopic medial maxillectomy approach: a rare case report. Bali Medical Journal, 13(1), 615–618.




Search Panel

Mohammad Husni Thamrin
Google Scholar
BMJ Journal

Budi Sutikno
Google Scholar
BMJ Journal